Night shift work characteristics are associated with several elevated metabolic risk factors and immune cell counts in a cross-sectional study
altered expression of Cyp2e1 or conjugation enzymes 15,16 ) or environmental exposures (alcohol 17 , drugs 14,18 , or microbiome composition 19 )
In preclinical research it is linked to protection of the gastrointestinal lining, support of angiogenesis, and signaling involved in tendon and ligament healing
Once activated, these dendritic cells release interleukin-23, a cytokine that drives the differentiation and expansion of TH17 cells
These criteria are more stringent than the previous Rotterdam criteria, aiming to identify women with higher metabolic risks associated with PCOS (131)